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產品詳細

采用多波長激光對外泌體、病毒等納米材料樣品中的所有顆粒進行完整、詳細的分析。


外泌體、病毒和納米顆粒都具有較寬的粒徑分布,這使得傳統的納米顆粒追蹤分析 (NTA)儀無法準確測量它們的粒徑分布。ViewSizer 3000的三個激光器可同時工作,可在同一樣品中收集各種尺寸的最準確的分布和濃度信息。如果某一顆粒來自某一激光的散射光信號太強使檢測器達到飽和,軟件會自動使用來自較低功率激光器的數據來確保獲得最準確的尺寸和濃度信息。另一方面,當來自某一激光的散射光信號太弱而無法檢測時,軟件會使用更高功率激光的數據來準確跟蹤顆粒。


交叉污染是所有分析中都存在的問題。簡化清潔意味著徹底清潔。易于拆卸的樣品池可以拆卸以進行快速、徹底的清潔,從而獲得更好的數據。


擺脫傳統 NTA 的限制


準確靈敏的分析,無交叉污染


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概要


ViewSizer 3000 使用納米顆粒追蹤分析技術 (NTA) 的最新進展來準確確定顆粒屬性!


粒徑測量范圍:10 nm- 15μm,具體范圍取決于樣品

ViewSizer 通過多激光納米顆粒追蹤分析技術 (NTA) 得到顆粒粒徑及粒徑分布。多個激光器可分析同一樣品中各種不同尺寸的顆粒,分辨率更高。

濃度測量范圍:5 x 106 - 2 x 108 顆/mL

NTA 可用于對測量體積中的顆粒進行計數。該測量方法可校正粒徑對有效測量體積的影響。

無交叉污染

樣品池可完全拆卸,拆卸后清洗更方便徹底。拆卸、清潔和重新組裝比沖洗流通池更快。此外,配備多個樣品池可樣品測量通量,也可分配給共享(核心)設施中的各個小組。


ViewSizer 3000相關文獻:

Biological characterization using protein crystal measurements https://bioprocessintl.com/analytical/product-characterization/biological-characterization-using-protein-crystal-measurements/
A lipase-independent pathway of lipid release and immune modulation by adipocytes https://science.sciencemag.org/content/363/6430/989
Application of a novel new multispectral nanoparticle tracking technique https://iopscience.iop.org/article/10.1088/1361-6501/aab940/meta
Biophysical characterization of polydisperse liposomal adjuvant formulations https://doi.org/10.1016/j.bbrc.2020.05.156
Characterisation of particles in solution – a perspective on light scattering and comparative technologies https://doi.org/10.1080/14686996.2018.1517587
Cyclodextrin Reduces Intravenous Toxicity of a Model Compound https://doi.org/10.1016/j.xphs.2019.01.004
Development and anti-Candida evaluation of the vaginal delivery system of amphotericin B nanosuspension-loaded thermogel https://doi.org/10.1080/1061186X.2018.1434660
Electrochemical sensor based on F,N-doped carbon dots decorated laccase for detection of catechol https://doi.org/10.1016/j.jelechem.2019.03.071
Light scattering by pure water and seawater: the depolarization ratio and its variation with salinity https://doi.org/10.1364/AO.58.000991
Lipid Nanoparticle-Delivered Chemically Modified mRNA Restores Chloride Secretion in Cystic Fibrosis https://doi.org/10.1016/j.ymthe.2018.05.014
Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells https://doi.org/10.1038/s41598-020-67039-w
Multifunctional Nanocomposites Based on Liposomes and Layered Double Hydroxides Conjugated with Glycylsarcosine for Efficient Topical Drug Delivery to the Posterior Segment of the Eye https://doi.org/10.1021/acs.molpharmaceut.8b01136
Particle size analysis of polydisperse liposome formulations with a novel multispectral advanced nanoparticle tracking technology https://doi.org/10.1016/j.ijpharm.2019.06.013
Review of nanoparticles in ultrapure water: definitions and current metrologies for detection and control https://www.ultrapuremicro.com/articles/review-of-nanoparticles-in-ultrapure-water-definitions-and-current-metrologies-for-detection-and-control
Spark erosion as a high-throughput method for producing bimodal nanostructured 316L stainless steel powder https://doi.org/10.1016/j.powtec.2018.01.012
Synthesis and Characterization of EGFR-Targeted Immunoporphysomes http://hdl.handle.net/1807/89548
Synthesis of Ultrasmall Synthetic Melanin Nanoparticles by UV Irradiation in Acidic and Neutral Conditions https://pubs.acs.org/doi/abs/10.1021/acsabm.9b00747
Nanoparticle Tracking Analysis for the Quantification and Size Determination of Extracellular Vesicles | Protocol (jove.com) https://doi.org/10.3791/62447
Isolation and characterization of EV in Saliva of Children with Asthma https://evcna.com/article/view/3962
Spinal cord injury alters microRNA and CD81+ exosome levels in plasma extracellular nanoparticles with neuroinflammatory potential https://doi.org/10.1016/j.bbi.2020.12.007
Skeletal muscle tissue secretes more extracellular vesicles than white adipose tissue and myofibers are a major source ex vivo but not in vivo https://doi.org/10.1101/2020.09.27.313932
Human milk extracellular vesicle miRNA expression and associations with maternal characteristics in a population-based cohort from the Faroe Islands https://www.nature.com/articles/s41598-021-84809-2
Purification of Cas9 - RNA Complexes by Ultrafiltration https://doi.org/10.1002/btpr.3104


配置

測量范圍

10 nm - 15 μm

典型樣品體積

350 μL - 1.25 mL

典型樣品濃度(取決于樣品)

5 x 106 to 2x108 顆/mL

樣品溫度范圍(可控)

10° C - 50° C +/- 0.1° C

外觀尺寸

55 cm W x 66 cm D x 35 cm H

重量

27 kg

工作環境

15° C - 30° C,濕度 < 85% RH